![]() ![]() Roche said that among the most important milestones for the Diagnostics division in the fourth quarter of 2022, it shared positive outcomes of the STRONG-HF study, which leveraged its Elecsys NT-proBNP biomarker, in patients hospitalized with acute heart failure. Pathology Lab revenue growth across all regions was driven mainly by sales increases in the advanced staining and the companion diagnostics businesses. and Europe, was offset by a higher demand in emerging geographic markets. The continued contraction of the blood glucose monitoring market, mainly in the U.S. The decrease was partly offset by growth in the base business across the portfolio.ĭiabetes Care sales decreased because of the effect of the resolution of a rebate dispute in 2021. Molecular Lab revenues decreased in 2022 due to lower COVID-19-related sales in the North America and EMEA regions. Demand for the Cobas SARS-CoV-2 & Influenza A/B assays also increased, and the largest contribution came from the Asia-Pacific and North America regions, according to Roche. In the Point of Care business, SARS-CoV-2 Rapid Antigen tests continued to be the main growth driver. Sales grew across all regions but most growth was seen in the Asia-Pacific Europe, the Middle East, and Africa (EMEA) and Latin America regions. These tools will help monitor the phytosanitary status of rice seeds to avoid the dissemination of Pantoea spp.Immunoassays, such as cardiac and oncology tests, and clinical chemistry products were the main growth drivers in the Core Lab diagnostics segment. Two diagnostic tools have been therefore developed: one that detects all known Pantoea species and another one that is specific for P. The goal of this work was to overcome the above difficulties and facilitate a quick and cost-effective diagnosis of the bacteria in rice leaves and paddy fields. However, LAMP has so far not been applied to rice/ Pantoea spp., neglected pathosystems that are wide-spread and important in Africa (12, 14). It has been used for highly specific and sensitive DNA amplification to detect various pathogens, including viruses, bacteria, protozoa and fungi. LAMP has several advantages, such as portability, simplicity and cost-efficiency because the reaction can be carried out in a water bath or heating block. The results of LAMP reactions can be detected without electrophoretic separation but by visualization of turbidity, fluorescence or a color change thanks to a metal ion indicator. The technique uses the thermostable Bst DNA polymerase for reliable and fast polymerization and operates under isothermal conditions at relatively high temperature. Isothermal loop-mediated amplification (LAMP) is a relatively simple technique that facilitates rapid amplification of DNA and has a high level of sensitivity and specificity at low cost. However, their use is complex, time consuming, expensive and cannot be deployed outside the laboratory. A semi-selective medium for their isolation and identification has also been developed. New diagnostic tools have been developed, such as simplex and multiplex PCR schemes able of identifying the three major Pantoea species affecting rice plants. Thus, measures need to be taken to limit the pathogens' dispersion and robust diagnostic tools are required for rapid and cheap diagnosis that can be used in the field as well as in routine screening of seed lots. are seed-transmitted and thus pose a significant threat to interstate and continental seed exchanges. Collectively, they cause various diseases and symptoms, such as leaf blight and dieback, red streak, black spot, necrosis, bacterial spot, tumors, rot center, stem necrosis, leaf rot, decay of seed and Stewart's wilt. stewartii on rice plants and seeds in Sub-Saharan Africa. wallisii, have been widely reported as plant pathogens, ,, with P. The Pantoea genus is composed of several species characterized by their ubiquity and versatility in their interactions with living organisms and the environment. ![]()
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